Determination of Corynebacterium diphtheriae toxigenicity by a colorimetric tissue culture assay.

Chinese hamster ovary (CHO) cell cultures in microtiter wells are sensitive to growth inhibition and killing by picogram quantities of diphtheria toxin. In the absence of biologically active toxin, the CHO cell culture produces sufficient acidic metabolites to change the phenol red pH indicator from...

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Bibliographic Details
Main Authors: Murphy, J R, Bacha, P, Teng, M
Format: Artigo
Language:Inglês
Published: 1978
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC274864/
https://ncbi.nlm.nih.gov/pubmed/415068
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