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The role of TGF-β mediated tumor-stroma interactions in prostate cancer progression: an integrative approach
We have implemented a hybrid cellular automata (HCA) model based upon the structure of human prostate that recapitulates key interactions in nascent tumor foci between tumor cells and adjacent stroma. Model simulations demonstrate how stochastic interactions between tumor cells and stroma may lead t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748342/ https://ncbi.nlm.nih.gov/pubmed/19706777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3957 |
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