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A Highly Active Catalyst for Pd-Catalyzed Amination Reactions: Cross-Coupling Reactions Using Aryl Mesylates and the Highly Selective Monoarylation of Primary Amines Using Aryl Chlorides

[Image: see text] A catalyst system based on a new biarylmonophosphine ligand (BrettPhos) that shows excellent reactivity for C–N cross-coupling reactions is reported. This catalyst system enables the use of aryl mesylates as a coupling partner in C–N bond-forming reactions. Additionally, the use of...

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Hlavní autoři: Fors, Brett P., Watson, Donald A., Biscoe, Mark R., Buchwald, Stephen L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748321/
https://ncbi.nlm.nih.gov/pubmed/18798626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8055358
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