Functional census of mutation sequence spaces: The example of p53 cancer rescue mutants

Many biomedical problems relate to mutant functional properties across a sequence space of interest, e.g., flu, cancer, and HIV. Detailed knowledge of mutant properties and function improves medical treatment and prevention. A functional census of p53 cancer rescue mutants would aid the search for c...

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Detalhes bibliográficos
Main Authors: Danziger, Samuel A., Swamidass, S. Joshua, Zeng, Jue, Dearth, Lawrence R., Lu, Qiang, Chen, Jonathan H., Cheng, Jainlin, Hoang, Vinh P., Saigo, Hiroto, Luo, Ray, Baldi, Pierre, Brachmann, Rainer K., Lathrop, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748235/
https://ncbi.nlm.nih.gov/pubmed/17048398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TCBB.2006.22
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