Predicting Positive p53 Cancer Rescue Regions Using Most Informative Positive (MIP) Active Learning

Many protein engineering problems involve finding mutations that produce proteins with a particular function. Computational active learning is an attractive approach to discover desired biological activities. Traditional active learning techniques have been optimized to iteratively improve classifie...

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Detalhes bibliográficos
Main Authors: Danziger, Samuel A., Baronio, Roberta, Ho, Lydia, Hall, Linda, Salmon, Kirsty, Hatfield, G. Wesley, Kaiser, Peter, Lathrop, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742196/
https://ncbi.nlm.nih.gov/pubmed/19756158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000498
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