Caricamento...

De Novo Mutation in POLG Leads to Haplotype Insufficiency and Alpers Syndrome

Mutations in POLG are a major contributor to pediatric and adult mitochondrial diseases. However, the consequences of many POLG mutations are not well understood. We investigated the molecular cause of Alpers syndome in a patient harboring the POLG mutations A467T in trans with c.2157+5_+6 gc→ag in...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Chan, Sherine S. L., Naviaux, Robert K., Basinger, Alice A., Casas, Kari A., Copeland, William C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748142/
https://ncbi.nlm.nih.gov/pubmed/19501198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2009.05.002
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !