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On the feasibility of visualizing ultrasmall gold labels in biological specimens by STEM tomography

Labeling with heavy atom clusters attached to antibody fragments is an attractive technique for determining the 3D distribution of specific proteins in cells using electron tomography. However, the small size of the labels makes them very difficult to detect by conventional bright-field electron tom...

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Detalhes bibliográficos
Main Authors: Sousa, A. A., Aronova, M. A., Kim, Y. C., Dorward, L. M., Zhang, G., Leapman, R. D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748118/
https://ncbi.nlm.nih.gov/pubmed/17689263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2007.06.006
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