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On the feasibility of visualizing ultrasmall gold labels in biological specimens by STEM tomography
Labeling with heavy atom clusters attached to antibody fragments is an attractive technique for determining the 3D distribution of specific proteins in cells using electron tomography. However, the small size of the labels makes them very difficult to detect by conventional bright-field electron tom...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748118/ https://ncbi.nlm.nih.gov/pubmed/17689263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2007.06.006 |
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