Molecular Mechanism of BST2/Tetherin Downregulation by K5/MIR2 of Kaposi's Sarcoma-Associated Herpesvirus

K3/MIR1 and K5/MIR2 of Kaposi's sarcoma-associated herpesvirus (KSHV) are viral members of the membrane-associated RING-CH (MARCH) ubiquitin ligase family and contribute to viral immune evasion by directing the conjugation of ubiquitin to immunostimulatory transmembrane proteins. In a quantitat...

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Autors principals: Mansouri, Mandana, Viswanathan, Kasinath, Douglas, Janet L., Hines, Jennie, Gustin, Jean, Moses, Ashlee V., Früh, Klaus
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748026/
https://ncbi.nlm.nih.gov/pubmed/19605472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00597-09
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