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Wild-Type p53 Enhances Efficiency of Simian Virus 40 Large-T-Antigen-Induced Cellular Transformation

Abortive infection of BALB/c mouse embryo fibroblasts differing in p53 gene status (p53(+/+) versus p53(−/)(−)) with simian virus 40 (SV40) revealed a quantitatively and qualitatively decreased transformation efficiency in p53(−/−) cells compared to p53(+/+) cells, suggesting a supportive effect of...

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Bibliografiske detaljer
Main Authors: Hermannstädter, Andrea, Ziegler, Christine, Kühl, Marion, Deppert, Wolfgang, Tolstonog, Genrich V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748005/
https://ncbi.nlm.nih.gov/pubmed/19625393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00174-09
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