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The Size of the Viral Inoculum Contributes to the Outcome of Hepatitis B Virus Infection
The impact of virus dose on the outcome of infection is poorly understood. In this study we show that, for hepatitis B virus (HBV), the size of the inoculum contributes to the kinetics of viral spread and immunological priming, which then determine the outcome of infection. Adult chimpanzees were in...
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Hauptverfasser: | , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
American Society for Microbiology (ASM)
2009
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748002/ https://ncbi.nlm.nih.gov/pubmed/19625407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00867-09 |
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