Toll-Like Receptor 3 Mediates Establishment of an Antiviral State against Hepatitis C Virus in Hepatoma Cells

Toll-like receptor-3 (TLR3) senses double-stranded RNA, initiating signaling that activates NF-κB and interferon regulatory factor 3 (IRF-3), thereby inducing the synthesis of proinflammatory cytokines, type I interferons, and numerous interferon-stimulated genes (ISGs). This pathway has not been ex...

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Detalhes bibliográficos
Main Authors: Wang, Nan, Liang, Yuqiong, Devaraj, Santhana, Wang, Jie, Lemon, Stanley M., Li, Kui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747996/
https://ncbi.nlm.nih.gov/pubmed/19625408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01125-09
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