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The protective and destructive roles played by molecular chaperones during ERAD (endoplasmic-reticulum-associated degradation)
Over one-third of all newly synthesized polypeptides in eukaryotes interact with or insert into the membrane or the lumenal space of the ER(endoplasmic reticulum), an event that is essential for the subsequent folding, post-translational modification, assembly and targeting of these proteins. Conseq...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747773/ https://ncbi.nlm.nih.gov/pubmed/17521290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061890 |
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