A Cholesterol Biosynthesis Inhibitor Blocks Staphylococcus aureus Virulence

Staphylococcus aureus produces hospital- and community-acquired infections, with methicillin-resistant S. aureus posing a serious public health threat. The golden carotenoid pigment of S. aureus, staphyloxanthin, promotes resistance to reactive oxygen species and host neutrophil-based killing, and e...

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Bibliographic Details
Main Authors: Liu, Chia-I, Liu, George Y., Song, Yongcheng, Yin, Fenglin, Hensler, Mary E., Jeng, Wen-Yin, Nizet, Victor, Wang, Andrew H.-J., Oldfield, Eric
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747771/
https://ncbi.nlm.nih.gov/pubmed/18276850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1153018
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