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Abrogation of IL-6-mediated JAK signalling by the cyclopentenone prostaglandin 15d-PGJ(2) in oral squamous carcinoma cells

Cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) exerts antineoplastic effects on various types of human cancer. We recently showed that treatment with 15d-PGJ(2) induces apoptosis accompanied by downregulation of the oncogenic signal transducer and activator of transcription 3 (Stat...

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Detalhes bibliográficos
Main Authors: Siavash, H, Nikitakis, N G, Sauk, J J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747713/
https://ncbi.nlm.nih.gov/pubmed/15316561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602055
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