Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells

Activation of poly(ADP-ribose) polymerase-1 (PARP1) has been shown to mediate cell death induced by genotoxic stimuli. The role of poly(ADP-ribose) glycohydrolase (PARG), the enzyme responsible for polymer degradation, has been largely unexplored in the regulation of cell death. Using lentiviral gen...

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Detalhes bibliográficos
Main Authors: Erdélyi, Katalin, Bai, Péter, Kovács, István, Szabó, Éva, Mocsár, Gábor, Kakuk, Annamária, Szabó, Csaba, Gergely, Pál, Virág, László
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2009
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747681/
https://ncbi.nlm.nih.gov/pubmed/19571039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-133264
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