Human Cytomegalovirus Suppresses Type I Interferon Secretion by Plasmacytoid Dendritic Cells through Its Interleukin 10 Homolog

Type I interferons (IFNs) are innate cytokines with potent antiviral and immunoregulatory activities. It remains unclear how human cytomegalovirus (HCMV) can establish persistence in the face of these strongly antagonistic cytokines. In this study, we confirm that IFN-α efficiently suppresses the pe...

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Hlavní autoři: Chang, W. L. William, Barry, Peter A., Szubin, Richard, Wang, Dai, Baumgarth, Nicole
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747589/
https://ncbi.nlm.nih.gov/pubmed/19524994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.05.013
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