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Human Cytomegalovirus Suppresses Type I Interferon Secretion by Plasmacytoid Dendritic Cells through Its Interleukin 10 Homolog

Type I interferons (IFNs) are innate cytokines with potent antiviral and immunoregulatory activities. It remains unclear how human cytomegalovirus (HCMV) can establish persistence in the face of these strongly antagonistic cytokines. In this study, we confirm that IFN-α efficiently suppresses the pe...

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Bibliografiske detaljer
Main Authors: Chang, W. L. William, Barry, Peter A., Szubin, Richard, Wang, Dai, Baumgarth, Nicole
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747589/
https://ncbi.nlm.nih.gov/pubmed/19524994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.05.013
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