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Human Cytomegalovirus Suppresses Type I Interferon Secretion by Plasmacytoid Dendritic Cells through Its Interleukin 10 Homolog

Type I interferons (IFNs) are innate cytokines with potent antiviral and immunoregulatory activities. It remains unclear how human cytomegalovirus (HCMV) can establish persistence in the face of these strongly antagonistic cytokines. In this study, we confirm that IFN-α efficiently suppresses the pe...

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Detalhes bibliográficos
Main Authors: Chang, W. L. William, Barry, Peter A., Szubin, Richard, Wang, Dai, Baumgarth, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747589/
https://ncbi.nlm.nih.gov/pubmed/19524994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.05.013
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