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Human Cytomegalovirus-Encoded Interleukin-10 Homolog Inhibits Maturation of Dendritic Cells and Alters Their Functionality

Interleukin-10 (IL-10) suppresses the maturation and cytokine production of dendritic cells (DCs), key regulators of adaptive immunity, and prevents the activation and polarization of naïve T cells towards protective gamma interferon-producing effectors. We hypothesized that human cytomegalovirus (H...

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Библиографические подробности
Главные авторы: Chang, W. L. William, Baumgarth, Nicole, Yu, Dong, Barry, Peter A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC479089/
https://ncbi.nlm.nih.gov/pubmed/15280480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8720-8731.2004
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