Human Cytomegalovirus-Encoded Interleukin-10 Homolog Inhibits Maturation of Dendritic Cells and Alters Their Functionality

Interleukin-10 (IL-10) suppresses the maturation and cytokine production of dendritic cells (DCs), key regulators of adaptive immunity, and prevents the activation and polarization of naïve T cells towards protective gamma interferon-producing effectors. We hypothesized that human cytomegalovirus (H...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Chang, W. L. William, Baumgarth, Nicole, Yu, Dong, Barry, Peter A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2004
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479089/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15280480/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.16.8720-8731.2004
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