Centromere specific assembly of CENP-A nucleosomes is mediated by HJURP

The centromere is responsible for accurate chromosome segregation. Mammalian centromeres are specified epigenetically, with all active centromeres containing centromere specific chromatin in which CENP-A replaces histone H3 within the nucleosome. The proteins responsible for assembly of human CENP-A...

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Main Authors: Foltz, Daniel R., Jansen, Lars E.T., Bailey, Aaron O., Yates, John R., Bassett, Emily A., Wood, Stacey, Black, Ben E., Cleveland, Don W.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747366/
https://ncbi.nlm.nih.gov/pubmed/19410544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.02.039
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