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Efficient Enantio- and Diastereo-divergent Synthesis of Poison-frog Alkaloids 251O and trans-223B

An efficient and flexible synthesis of poison-frog alkaloids 251O and trans-223B has been achieved using for both alkaloids an enantiodivergent process starting from the common lactam 1. The relative stereochemistry of 251O and trans-223B was determined to be 7 (R = n- C(7)H(15), R’ = n-Pr) and 14 b...

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Detaylı Bibliyografya
Asıl Yazarlar: Toyooka, Naoki, Zhou, Dejun, Nemoto, Hideo, Tezuka, Yasuhiro, Kadota, Shigetoshi, Andriamaharavo, Nirina R., Garraffo, H. Martin, Spande, Thomas F., Daly, John W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747258/
https://ncbi.nlm.nih.gov/pubmed/19637860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo901100m
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