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Efficient Enantio- and Diastereo-divergent Synthesis of Poison-frog Alkaloids 251O and trans-223B
An efficient and flexible synthesis of poison-frog alkaloids 251O and trans-223B has been achieved using for both alkaloids an enantiodivergent process starting from the common lactam 1. The relative stereochemistry of 251O and trans-223B was determined to be 7 (R = n- C(7)H(15), R’ = n-Pr) and 14 b...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747258/ https://ncbi.nlm.nih.gov/pubmed/19637860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo901100m |
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