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C2′-endo nucleotides as molecular timers suggested by the folding of an RNA domain

A striking and widespread observation is that higher-order folding for many RNAs is very slow, often requiring minutes. In some cases, slow folding reflects the need to disrupt stable, but incorrect, interactions. However, a molecular explanation for slow folding in most RNAs is unknown. The specifi...

詳細記述

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書誌詳細
主要な著者: Mortimer, Stefanie A., Weeks, Kevin M.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747169/
https://ncbi.nlm.nih.gov/pubmed/19717440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901319106
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