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Single molecule conformational analysis of DNA G-quadruplexes

Single molecule fluorescence resonance energy transfer (FRET) can be employed to study conformational heterogeneity and real-time dynamics of biological macromolecules. Here we present single molecule studies on human genomic DNA G-quadruplex sequences that occur in the telomeres and in the promoter...

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Autors principals: Shirude, Pravin S., Balasubramanian, Shankar
Format: Artigo
Idioma:Inglês
Publicat: Editions Scientifiques Elsevier 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746965/
https://ncbi.nlm.nih.gov/pubmed/18295608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2008.01.015
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