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Blockade of androgen receptors is sufficient to alter the sexual differentiation of the substantia nigra pars reticulata seizure-controlling network

The substantia nigra pars reticulata (SNR) controls seizures in a sex-specific manner. At postnatal day 15 (P15), SNR infusion of GABA(A) receptor agonist muscimol have proconvulsant effects in males but not in females. In males, administration of an androgen receptor antagonist flutamide between P0...

詳細記述

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書誌詳細
主要な著者: Heida, James G., Velíšková, Jana, Moshé, Solomon L.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746950/
https://ncbi.nlm.nih.gov/pubmed/18367425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1684/epd.2008.0160
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