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BCL6 Cooperates with CD40 Stimulation and Loss of p53 Function to Rapidly Transform Primary B cells

The BCL6 transcriptional repressor protein has been shown to promote B cell lymphoma in transgenic mouse models. The mechanism by which BCL6 transforms primary B cells is unclear, although repression of the p53 tumor suppressor is thought to play a role. Here we show that BCL6 has critical oncogene...

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Hlavní autoři: Kusam, Saritha, Munugalavadla, Veerendra, Sawant, Deepali, Dent, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746643/
https://ncbi.nlm.nih.gov/pubmed/19405121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24450
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