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Claudin-16 affects transcellular Cl(−) secretion in MDCK cells

Claudin-16 (paracellin-1) is a tight junction protein localized mainly in the thick ascending limb of Henle's loop and also in the distal nephron. Its defect causes familial hypomagnesaemia with hypercalciuria and nephrocalcinosis. This had been taken as an indication that claudin-16 conveys pa...

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Main Authors: Günzel, Dorothee, Amasheh, Salah, Pfaffenbach, Sandra, Richter, Jan F, Kausalya, P Jaya, Hunziker, Walter, Fromm, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746610/
https://ncbi.nlm.nih.gov/pubmed/19528248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.173401
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