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Development of an in-vitro model system to investigate the mechanism of muscle protein catabolism induced by proteolysis-inducing factor

The mechanism of muscle protein catabolism induced by proteolysis-inducing factor, produced by cachexia-inducing murine and human tumours has been studied in vitro using C(2)C(12) myoblasts and myotubes. In both myoblasts and myotubes protein degradation was enhanced by proteolysis-inducing factor a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gomes-Marcondes, M C C, Smith, H J, Cooper, J C, Tisdale, M J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746596/
https://ncbi.nlm.nih.gov/pubmed/12085214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600236
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