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Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE

Multiple sclerosis is an inflammatory disease of the central nervous system that begins as a relapsing-remitting disease (RRMS) and is followed by a progressive phase (SPMS). The progressive phase causes the greatest disability and has no effective therapy, but the processes that drive SPMS are most...

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Detalhes bibliográficos
Main Authors: Farez, Mauricio F, Quintana, Francisco J, Gandhi, Roopali, Izquierdo, Guillermo, Lucas, Miguel, Weiner, Howard L
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746562/
https://ncbi.nlm.nih.gov/pubmed/19684606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1775
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