Arginine methylation of Piwi proteins, catalyzed by dPRMT5, is required for Ago3 and Aub stability

Piwi family proteins are essential for germline development and bind piwi-interacting RNAs (piRNAs 1 2 3). The grandchildless gene aub of Drosophila melanogaster encodes the piRNA-binding protein Aub that is essential for formation of primordial germ cells (PGCs) 4. Here we report that mouse, Xenopu...

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Bibliografiset tiedot
Päätekijät: Kirino, Yohei, Kim, Namwoo, de Planell-Saguer, Mariàngels, Khandros, Eugene, Chiorean, Stephanie, Klein, Peter S., Rigoutsos, Isidore, Jongens, Thomas A., Mourelatos, Zissimos
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746449/
https://ncbi.nlm.nih.gov/pubmed/19377467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1872
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