Llwytho...

Local and Global Effects of a Cavity Filling Mutation in a Metastable Serpin

The serpins are an unusual class of protease inhibitors which fold to a metastable form and subsequently undergo a massive conformational change to a stable form when they inhibit their target proteases. The driving force for this conformational change has been extensively investigated by site direc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sengupta, Tanusree, Tsutsui, Yuko, Wintrode, Patrick L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746415/
https://ncbi.nlm.nih.gov/pubmed/19624115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900342d
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