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Relationship between circadian oscillations of Rev-erbα expression and intracellular levels of its ligand, heme
The nuclear hormone receptors, REV-ERBα [NR1D1] and REV-ERBβ [NR1D1], were recently demonstrated to be receptors for the porphyrin, heme. Heme regulates the ability of these receptors to repress transcription of their target genes via modulation of the affinity of the receptor's ligand binding...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746331/ https://ncbi.nlm.nih.gov/pubmed/18280802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.02.031 |
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