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The HIV-1 coat protein gp120 regulates cxcr4-mediated signaling in neural progenitor cells
We demonstrate that hCD4-primed gp120IIIB interacts with CXCR4 receptors expressed by postnatal mouse neural progenitor cells and elicits robust Ca(2+) signals. The chemokine SDF-1 acted as a chemoattractant and a mitogenic stimulus for these neural progenitor cells. Although hCD4/gp120 was not able...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746240/ https://ncbi.nlm.nih.gov/pubmed/15710459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2004.11.001 |
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