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Heme regulation of human cystathionine β-synthase activity: Insights from fluorescence and Raman spectroscopy
Cystathionine β-synthase (CBS) plays a central role in cysteine metabolism, and malfunction of the enzyme leads to homocystinuria, a devastating metabolic disease. CBS contains a pyridoxal 5′-phosphate (PLP) cofactor which catalyzes the synthesis of cystathionine from homocysteine and serine. Mammal...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746071/ https://ncbi.nlm.nih.gov/pubmed/19722721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja904468w |
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