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Mechanisms of inhibition of HIV replication by nonnucleoside reverse transcriptase inhibitors

The nonnucleoside reverse transcriptase (RT) inhibitors (NNRTIs) are a therapeutic class of compounds that are routinely used, in combination with other antiretroviral drugs, to treat HIV-1 infection. NNRTIs primarily block HIV-1 replication by preventing RT from completing reverse transcription of...

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Bibliographic Details
Main Authors: Sluis-Cremer, Nicolas, Tachedjian, Gilda
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745993/
https://ncbi.nlm.nih.gov/pubmed/18372072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2008.01.002
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