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Disruption of glutamate receptors at Shank-postsynaptic platform in Alzheimer's disease

Synaptic loss underlies the memory deficit of Alzheimer's disease (AD). The molecular mechanism is elusive; however, excitatory synapses organized by the postsynaptic density (PSD) have been used as targets for AD treatment. To identify pathological entities at the synapse in AD, synaptic prote...

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Detalles Bibliográficos
Main Authors: Gong, Yuesong, Lippa, Carol F., Zhu, Jinghua, Lin, Qishan, Rosso, Andrea L.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745956/
https://ncbi.nlm.nih.gov/pubmed/19635471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.07.056
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