Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival

BCL2 and MYC are oncogenes commonly deregulated in lymphomas. Concurrent BCL2 and MYC translocations (BCL2(+)/MYC(+)) were identified in 54 samples by karyotype and/or fluorescence in situ hybridization with the aim of correlating clinical and cytogenetic characteristics to overall survival. BCL2(+)...

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Main Authors: Johnson, Nathalie A., Savage, Kerry J., Ludkovski, Olga, Ben-Neriah, Susana, Woods, Ryan, Steidl, Christian, Dyer, Martin J. S., Siebert, Reiner, Kuruvilla, John, Klasa, Richard, Connors, Joseph M., Gascoyne, Randy D., Horsman, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2009
Assuntos:
Lymphoid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745846/
https://ncbi.nlm.nih.gov/pubmed/19597184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-212191
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