CD44v6 Dependence of Premetastatic Niche Preparation by Exosomes

The metastasizing capacity of the rat pancreatic adenocarcinoma BSp73ASML (ASML(wt)) is strikingly reduced by a knockdown of CD44v4-v7 (ASML(kd)). We used this model to analyze the role of the CD44 variant isoform (CD44v) in (pre)metastatic niche formation. Intrafootpad injections of ASML(wt)-, but...

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Bibliografiska uppgifter
Huvudupphovsmän: Jung, Thorsten, Castellana, Donatello, Klingbeil, Pamela, Hernández, Ines Cuesta, Vitacolonna, Mario, Orlicky, David J, Roffler, Steve R, Brodt, Pnina, Zöller, Margot
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press Inc. 2009
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745675/
https://ncbi.nlm.nih.gov/pubmed/19794968
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