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Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice

Polyethylene glycol (PEG)-coated (pegylated) gold nanoparticles (AuNPs) have been proposed as drug carriers and diagnostic contrast agents. However, the impact of particle characteristics on the biodistribution and pharmacokinetics of pegylated AuNPs is not clear. We investigated the effects of PEG...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Guodong, Yang, Zhi, Lu, Wei, Zhang, Rui, Huang, Qian, Tian, Mei, Li, Li, Liang, Dong, Li, Chun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745599/
https://ncbi.nlm.nih.gov/pubmed/19131103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.12.038
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