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Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice

Polyethylene glycol (PEG)-coated (pegylated) gold nanoparticles (AuNPs) have been proposed as drug carriers and diagnostic contrast agents. However, the impact of particle characteristics on the biodistribution and pharmacokinetics of pegylated AuNPs is not clear. We investigated the effects of PEG...

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Detalhes bibliográficos
Main Authors: Zhang, Guodong, Yang, Zhi, Lu, Wei, Zhang, Rui, Huang, Qian, Tian, Mei, Li, Li, Liang, Dong, Li, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745599/
https://ncbi.nlm.nih.gov/pubmed/19131103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.12.038
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