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Using structural bioinformatics to investigate the impact of non synonymous SNPs and disease mutations: scope and limitations
BACKGROUND: Linking structural effects of mutations to functional outcomes is a major issue in structural bioinformatics, and many tools and studies have shown that specific structural properties such as stability and residue burial can be used to distinguish neutral variations and disease associate...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745591/ https://ncbi.nlm.nih.gov/pubmed/19758473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-S8-S9 |
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