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Tat Peptide Is Capable of Importing Large Nanoparticles Across Nuclear Membrane in Digitonin Permeabilized Cells

Understanding the capabilities and limitations of nuclear import is crucial to efficient delivery of macromolecules and nanoparticles for diagnosis and targeted therapy of diseases. Here we report the Tat peptide-mediated import of different cargos into cell nucleus, including dye-labeled streptavid...

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Autors principals: Nitin, Nitin, LaConte, Leslie, Rhee, Won Jong, Bao, Gang
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745486/
https://ncbi.nlm.nih.gov/pubmed/19657743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-009-9768-0
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