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TGFβ Regulation of Membrane Mucin Muc4 via Proteosome Degradation
Muc4 is a heterodimeric membrane mucin implicated in epithelial differentiation and tumor progression. It is expressed from a single gene as a 300 kDa precursor protein which is cleaved in the endoplasmic reticulum to its two subunits. Our previous work has shown that Muc4 is regulated by TGFβ, whic...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745306/ https://ncbi.nlm.nih.gov/pubmed/19388004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22177 |
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