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THE FIRST TRANSMEMBRANE REGION OF THE BETA CHAIN STABILIZES THE TETRAMERIC FcεRI COMPLEX

The family of activating immune receptors stabilizes via the 3-helix assembly principle. A charged basic transmembrane residue interacts with two charged acidic transmembrane residues and forms a 3-helix interface to stabilize receptor complexes in the lipid bilayer. One family member, the high affi...

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Bibliographic Details
Main Authors: Singleton, Theresa E., Platzer, Barbara, Dehlink, Eleonora, Fiebiger, Edda
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745130/
https://ncbi.nlm.nih.gov/pubmed/19406478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.03.023
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