Loading...
Decreased secretion and unfolded protein response up-regulation are correlated with intracellular retention for single-chain antibody variants produced in yeast
Heterologous protein expression can easily overwhelm a cell's capacity to properly fold protein, initiating the unfolded protein response (UPR), and resulting in a loss of protein expression. In the current model of the unfolded protein response, the chaperone BiP modulates the activation of th...
Na minha lista:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2744959/ https://ncbi.nlm.nih.gov/pubmed/19415776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.22376 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|