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CD5-CK2 Binding/Activation Deficient Mice Are Resistant to EAE: Protection is Associated With Diminished Populations of IL-17 Expressing T-cells in the CNS

Regulating the differentiation and persistence of encephalitogenic T-cells is critical for the development of experimental autoimmune encephalomyelitis (EAE). We recently reported that CD5 has an engagement-dependent prosurvival activity in T-cells which had a direct role in the induction and progre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Axtell, Robert C., Xu, Liang, Barnum, Scott R., Raman, Chander
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744950/
https://ncbi.nlm.nih.gov/pubmed/17142752
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