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Vaccination with tumor cells pulsed with foreign peptide induces immunity to the tumor itself

EMT-6 mammary carcinoma and B16 melanoma (B16M) cells are lethal and barely immunogenic in syngeneic BALB/c and C57BL/6 mice, respectively. We show that mice vaccinated with tumor cells pulsed with a MHC class I-restricted peptide develop a T cell response, not only to the peptide, but also to the u...

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Detalhes bibliográficos
Main Authors: Schlingmann, Tobias R., Rininsland, Frauke H., Bartholomae, Wolf C., Kuekrek, Haydar, Lehmann, Paul V., Tary-Lehmann, Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744850/
https://ncbi.nlm.nih.gov/pubmed/19589730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2009.06.004
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