Lack of Disease Specificity Limits the Usefulness of In Vitro Costimulation in HIV- and HCV-Infected Patients

Measurements of antigen-specific T cell responses in chronic diseases are limited by low frequencies of antigen-specific cells in the peripheral blood. Therefore, attempts have been made to add costimulatory molecules such as anti-CD28 or IL-7/IL-15 to ELISPOT assays to increase sensitivity. While t...

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Autores principales: Kuerten, Stefanie, Schlingmann, Tobias R., Rajasalu, Tarvo, Angelov, Doychin N., Lehmann, Paul V., Tary-Lehmann, Magdalena
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486353/
https://ncbi.nlm.nih.gov/pubmed/18670652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/590941
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