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Shp2 Acts Downstream of SDF-1α/CXCR4 in Guiding Granule Cell Migration During Cerebellar Development

Shp2 is a non-receptor protein tyrosine phosphatase containing two Src homology 2 (SH2) domains that is implicated in intracellular signaling events controlling cell proliferation, differentiation and migration. To examine the role of Shp2 in brain development, we created mice with Shp2 selectively...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hagihara, Kazuki, Zhang, Eric E., Ke, Yue-Hai, Liu, Guofa, Liu, Jan-Jan, Rao, Yi, Feng, Gen-Sheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744846/
https://ncbi.nlm.nih.gov/pubmed/19635473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.07.029
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