Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

The chemokine stromal cell-derived factor 1, SDF-1, is an important regulator of leukocyte and hematopoietic precursor migration and pre-B cell proliferation. The receptor for SDF-1, CXCR4, also functions as a coreceptor for T-tropic HIV-1 entry. We find that mice deficient for CXCR4 die perinatally...

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Detalhes bibliográficos
Main Authors: Ma, Qing, Jones, Dan, Borghesani, Paul R., Segal, Rosalind A., Nagasawa, Takashi, Kishimoto, Tadamitsu, Bronson, Roderick T., Springer, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21358/
https://ncbi.nlm.nih.gov/pubmed/9689100
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