Transcytosis-Blocking Abs Elicited by an Oligomeric Immunogen Based on the Membrane Proximal Region of HIV-1 gp41 Target Non-Neutralizing Epitopes

CTB-MPR(649–684), a translational fusion protein consisting of cholera toxin B subunit (CTB) and residues 649–684 of gp41 membrane proximal region (MPR), is a candidate vaccine aimed at blocking early steps of HIV-1 mucosal transmission. Bacterially produced CTB-MPR(649–684) was purified to homogene...

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Main Authors: Matoba, Nobuyuki, Griffin, Tagan A., Mittman, Michele, Doran, Jeffrey D., Alfsen, Annette, Montefiori, David C., Hanson, Carl V., Bomsel, Morgane, Mor, Tsafrir S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744741/
https://ncbi.nlm.nih.gov/pubmed/18473785
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