Human Telomerase Reverse Transcriptase (hTERT) Q169 Is Essential for Telomerase Function In Vitro and In Vivo

BACKGROUND: Telomerase is a reverse transcriptase that maintains the telomeres of linear chromosomes and preserves genomic integrity. The core components are a catalytic protein subunit, the telomerase reverse transcriptase (TERT), and an RNA subunit, the telomerase RNA (TR). Telomerase is unique in...

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Detaylı Bibliyografya
Asıl Yazarlar: Wyatt, Haley D. M., Tsang, Allison R., Lobb, Deirdre A., Beattie, Tara L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744565/
https://ncbi.nlm.nih.gov/pubmed/19777057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007176
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